I prefer to use the right mouse button to bind actions to it.
Eg: i use right to toggle osd, left+wheel to seek, right+wheel to zoom, left+right+wheel to do long seeks and so on.
Standard mouses (with left,right and wheel controls) can use up to 16 actions that way; take a look to the local hotkeys window and try a combination.
All of the things i could think off are still usable by use pull down menu buttons from the main bar which, in fullscreen drops down as you move the mouse to the top part of the screen.
If you need to have fast access to an option; bind it to a mouse/wheel/key combination or just ask me for it.
Please, use github.